Engineering Research Seminar Series 2, 2013: Functional Analysis of Hyperthermophiles and their Application

Dr Takenori Satomura, University of Fukui, Japan

Date: 2013-03-07
Time: 12:00 to 13:00
Venue: Engineering Meeting Room 1, 5-4-22


Hyperthermophile grows at temperatures near or above the boiling point of water. These organisms have been isolated from marine and continental volcanic environments. The interest in hyperthermophiles has been rapidly expanding. The interest is focused on understanding the adaption mechanisms that allow the metabolism to function and the biomolecules, such as protein, enzyme, and DNA, to remain intact at extremely high temperature. Most hyperthermophiles belong to Archaea, the third domain of life, and evolutionary attention has been paid to their biomolecules because they may be the most slowly evolving or primitive group of microorganisms yet discovered. In addition, enzymes from the hyperthermophiles have a large biotechnological potential. Their thermostability is associated with a higher resistance to chemical denaturants (such as a solvent or guanidinium hydrochloride), and performing enzymatic reactions at high temperatures allows higher substrate concentrations, lower viscosity, fewer risks of microbial contaminations, and often higher reaction rates. This presentation focuses on the functional and structural properties of hyperthermophilic enzymes and their applications

About the Speaker

Dr Takenori Satomura is an Associate Professor in Department of Applied Chemistry and Biotechnology, Graduate School of Engineering, University of Fukui since 2011. Prior to joining the University, he worked as an Assistant professor at Yonago National College of Technology. Dr. Satomura has a PhD in Engineering  from University of Tokushima, Japan