Engineering Seminar Series 27_2013: Fabrication and Characterization of Multi-shell Oil Core Microcapsule via Complex Coacervation and Layer-by-layer Assembly

Mr Ho Kiang Wei, Chem Eng postgraduate student

Date: 2013-05-29
Time: 11:00 to 12:00
Venue: Engineering Meeting Room 1, 5-4-22


The aim of this research is to fabricate a core-shell structured microparticles containing liquid oil core, which are able to withstand spray drying stresses to give high process yield and powder of high oil loading and desirable properties for applications in the food, pharmaceutical and nutraceutical industries. Previous works include formation of protein/polysaccharide-based microcapsules using a complex coacervation method which were subsequently spray-dried to form powder. However, the microcapsules formed were ruptured easily during spray drying and the use of cross-linking agents which are toxic to strengthen the mechanical properties of the wall is a major hindrance to industries. In this work, polysaccharide-based microcapsules will be fabricated using Octenyl Succinic Anhydride (OSA) starch and chitosan via complex coacervation followed by layer-by-layer assembly of oppositely charged polyelectrolyte to tune the mechanical properties of the microcapsules. The relationships between the mechanical properties of the microcapsules and the spray drying performance as well as the resultant powder quality are the main knowledge gaps that will be addressed in this research. The mechanical properties of the microcapsules will be studied using atomic force microscopy technique and/or micro-manipulation method.

About the Speaker

Ho Kiang Wei graduated with a Bachelor of Engineering (Agricultural and Biosystems) from University Putra Malaysia,Serdang in 2011. He is currently pursuing a PhD in the School of Engineering in Monash University, under the supervision of A/P Chan Eng Seng as main supervisor and Prof. Tey Beng Ti as co-supervisor.