Seminar

Engineering Semianr Series 15_2010: Recent Key Findings on Extra-cellular Matrix of Connective Tissues and Implications for Engineering Biomimicking Structural Materials for

Dr Goh Kheng Lim, senior lecturer from School of Engineering, MUSC


Date: 2010-09-24
Time: 12:00 to 13:00
Venue: Tutorial room 9-5-04


Abstract

 

Extracellular matrix (ECM) of connective tissues, such as tendons and ligaments, comprise collagen fibrils strong in tension, reinforcing a weak hydrated proteoglycan-rich matrix as a mean of facilitating support for the tissue. This talk is intended to (1) present recent key findings on extracellular matrix of connective tissues that underpin the mechanism of stress transfer in ECM and (2) discuss implications of these findings for engineering biomimicking structural materials for sustainability. 

Extracellular matrix (ECM) of connective tissues, such as tendons and ligaments, comprise collagen fibrils strong in tension, reinforcing a weak hydrated proteoglycan-rich matrix as a mean of facilitating support for the tissue. This talk is intended to (1) present recent key findings on extracellular matrix of connective tissues that underpin the mechanism of stress transfer in ECM and (2) discuss implications of these findings for engineering biomimicking structural materials for sustainability.

About the Speaker

Dr Kheng-Lim Goh is a Chartered Physicist and Scientist. His PhD degree (University of Aberdeen) was in the area of Bioengineering. He has worked as a research assistant for Prof. Malcolm Pope to study the biomechanics of occupational low back pain at the Liberty Work Safe Centre (Aberdeen, 2001-2) and as a post-doc to investigate the mechanisms of ageing in extracellular matrix (ECM) of connective tissues (Stirling & Cardiff University, 2002-4). In 2005, he moved to Singapore to take up a faculty position as an Assistant Professor at the School of Chemical & Biomedical Engineering, Nanyang Technological University. In 2009, he was appointed as a Senior Lecturer in Mechanical Engineering at Monash University Malaysia. His current research interests include basic and applied studies on fibre composites, particularly on the development of biocomposites for biomedical applications. Dr Goh is a member of the editorial boards of the Journal of Mechanics in Medicine and Biology and the Journal of Medical Imaging and Health Informatics.