Engineering Seminar Series 28, 2010: Synthesis and Characterization of Chitosan-POSS Composite Microfibres

Dr Goh Kheng Lim, Senior lecturer, School of Engineering, MUSC

Date: 2010-12-09
Time: 12:00 to 13:00
Venue: 9504


Chitosan is a N-deacetyl derivative of chitin. Structurally the biopolymer can be molded into many useful shapes, such as beads, filaments, hydrogel and even films. Commercially, its biomedical properties, namely biocompatibility, biodegradability and cell eliciting, are often exploited for biomedical applications, such as medical gauze. Here, we describe a study to synthesize and characterize novel chitosan-based ribbon-like microfibres reinforced by inorganic aminopropylphenyl polyhedral oligomeric silsesquioxanes (POSS) crystallines. The results from this study suggest that these microfibres may find applications in tissue engineering as biomaterials, e.g. these microfibres may be laid out into a three-dimensional mesh-like scaffolds for guiding cells to form vascularised tissue in vivo to aid tissue repair.

About the Speaker

Dr Kheng-Lim Goh is a Chartered Physicist and Scientist. His PhD degree (University of Aberdeen) was in the area of Bioengineering. He has worked as a research assistant for Prof. Malcolm Pope to study the biomechanics of occupational low back pain at the Liberty Work Safe Centre (Aberdeen, 2001-2) and as a post-doc to investigate the mechanisms of ageing in extracellular matrix (ECM) of connective tissues (Stirling & Cardiff University, 2002-4). In 2005, he moved to Singapore to take up a faculty position as an Assistant Professor at the School of Chemical & Biomedical Engineering, Nanyang Technological University. In 2009, he was appointed as a Senior Lecturer in Mechanical Engineering at Monash University Malaysia. His current research interests include basic and applied studies on fibre composites, particularly on the development of biocomposites for biomedical applications. Dr Goh is a member of the editorial boards of the Journal of Mechanics in Medicine and Biology and the Journal of Medical Imaging and Health Informatics.